Professor Christou Selected to The Highly Cited Researchers List.

“Distinguished Professor George Christou is one of 204 chemists worldwide who have been selected for the�Highly Cited Researchers�list published in 2014 by Thompson Reuters. The list contains over 3200 researchers, spanning 21 broad fields of the sciences and social sciences, who have over the period 2002-2012, “earned the distinction by writing the greatest numbers of reports officially designated by Essential Science Indicators? as Highly Cited Papers – ranking among the top one percent most cited for their subject field and year of publication, earning them the mark of exceptional impact.”

Professor Christou Selected to The Highly Cited Researchers List.

“Distinguished Professor George Christou is one of 204 chemists worldwide who have been selected for the�Highly Cited Researchers�list published in 2014 by Thompson Reuters. The list contains over 3200 researchers, spanning 21 broad fields of the sciences and social sciences, who have over the period 2002-2012, “earned the distinction by writing the greatest numbers of reports officially designated by Essential Science Indicators? as Highly Cited Papers – ranking among the top one percent most cited for their subject field and year of publication, earning them the mark of exceptional impact.”

Professor Butcher Awarded 2014 Sloan Research Fellowship

“Congratulations to Professor Rebecca A. Butcher on being named a 2014 Sloan Research Fellow by the Alfred P. Sloan Foundation. The foundation seeks to stimulate fundamental research by early-career scientists and scholars of outstanding promise. Professor Butcher is one of only twenty-three chemists to receive this award in 2014. Sloan Fellows receive $50,000 for a two-year period to support their research goals.”

Aponick Group Research Highlighted in Nature Chemistry

“In the Aponick group, Flavio Cardoso has been studying the preparation of a new class of biaryl ligands for asymmetric catalysis. Biaryls containing 5-membered heterocycles were hypothesized to be excellent P,N-ligands, but their preparation as a single enantiomer required new design strategies. Cardoso and Aponick, with Khalil Abboud, recently published their new approach involving ground state stabilization of the chiral conformer as a�JACS�Communication. This work was recently highlighted in�Nature Chemistry�where it is noted that ?-stacking greatly increases the configurational stability of these biaryls, which function as highly enantioselective ligands in the asymmetric A3-coupling reaction. Full details can be found at:”

Aponick Group Research Highlighted in Nature Chemistry

“In the Aponick group, Flavio Cardoso has been studying the preparation of a new class of biaryl ligands for asymmetric catalysis. Biaryls containing 5-membered heterocycles were hypothesized to be excellent P,N-ligands, but their preparation as a single enantiomer required new design strategies. Cardoso and Aponick, with Khalil Abboud, recently published their new approach involving ground state stabilization of the chiral conformer as a�JACS�Communication. This work was recently highlighted in�Nature Chemistry�where it is noted that ?-stacking greatly increases the configurational stability of these biaryls, which function as highly enantioselective ligands in the asymmetric A3-coupling reaction. Full details can be found at:”

Prof. Butcher is named a New Scholar in Aging by the Ellison Medical Foundation

“Congratulations to Prof. Rebecca Butcher on being named one of 25 New Scholars in Aging by the Ellison Medical Foundation. The objective of the program is to support new investigators of outstanding promise in the basic biological sciences relevant to understanding lifespan development processes and age-related diseases. The award is $100,000 per year, for a four year period. Dr. Butcher’s award will support her work on the identification of chemical signals that influence development, metabolism, and lifespan in the model organism C. elegans.”

Merz Group Research Featured on JACS Cover

“A molecular dynamics study of the zinc sensing transcriptional repressor Staphylococcus aureus CzrA was featured on the cover of the Feb 22nd edition of the Journal of the American Chemical Society. CzrA is a member of the ArsR/SmtB family of metal sensor proteins and functions through a mechanism of allosteric negative regulation. The cover shows the protein undergoing a quaternary structural switch from a “closed” DNA-bound conformation to a more “open” conformation in response to Zn(II) binding. This disrupts the DNA-binding interface and reduces the binding affinity of CzrA for DNA and, ultimately, transcriptional de-repression. In collaboration with the Giedroc group at the University of Indiana, the Merz group used classical MD, QM/MM and QM/MM MD methods to investigate the molecular basis for the large conformational motions and the allosteric coupling free energy (~6 kcal/mol) associated with metal ion binding.”

UF Engineer Develops Full Color 3D Scanning Microscope

“Mr. Robert Harker, an Engineer working for Dr. Ion Ghiviriga in Chemistry’s own Nuclear Magnetic Resonance Lab was granted a US utility patent for the following new and useful invention: “Full Spectrum Lapidary 3D Image Scanner and Method,” US Patent 7840300 B2. These technologies are available free to any UF researcher and are in keeping with the innovation goals of the university. This patent could not have been issued without the extremely helpful support of the UF Office of Technology and Licensing. The inventor would like to express special thanks to Dr. Ion Ghiviriga, Mr. Bruce Clary, Mr. David Day, and Dr. Win Phillips. This novel invention uses polishing techniques to slowly polish or abrade away stepped layers of an object to be scanned. It is 100{3c0caad52c08e46b57c1dc946e6f87c810c2d6c46589b97ffcbbf8f3a9791f0d} sample destructive. The scanned object is cast into a contrasting resin which both hardens and provides a dark, light, or colored background for high contrast photography. The layers are digitally photographed stepwise to produce a record of internal structures. 2D digital images are reassembled using computer and software methods to produce exquisitely finely detailed 3D digital models of the solid internal structures in full color beyond the reach of most researchers.”