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James A. DeyrupProfessor Emeritus
Work Fax: 352-392-8758workfax Work Email: email@example.comINTERNET
Work University of Florida Department of Chemistry PO Box 117200 Gainesville FL 32611 work
Our chemistry focuses on total synthesis of biologically active molecules and the design of new synthetic methodology, including antibiotics, antitumor agents, tumor promoters, cytotoxic agents, anti-HIV and anti-leukemic compounds. The construction of these molecules uses novel synthetic intermediates such as tin ketyls, samarium ketyls and free radical cyclizations. Cycloadditions are used to form multiple rings in a single step with complete regio- and stereocontrol include carbonyl-ylide [3+2]-cycloadditions and [5+2]-cycloadditions with 3-oxidopyrylium intermediates.
Updated 4 years ago.