Steven D. Bruner

Professor University of FloridaChemistry – Chemical Biology Division
Work Phone: 352 392 0525 Website:
Department of Chemistry P.O. Box 117200 Gainesville Florida 32611 SFH 302E
Photo of Steven D. Bruner

Biographical Info

Structurally complex natural products, such as the medicinally relevant antibiotics vancomycin and erthromycin, are biosynthesized by large, macromolecular enzyme assemblies. These assemblies frequently orchestrate difficult and interesting chemical transformations t construct diverse molecular scaffolds. Our research group will use the tools of synthetic organic chemistry, enzymology and structural biology to dissect the mechanism of these systems. A detailed understanding of the biosynthesis of natural products will be extended to the development of new synthetic methodology and to the engineering of biological systems to produce novel molecules with desired properties.

Categories: all faculty, chemical biology, Chemical Biology Division, organic, research faculty, synthesis