WH Tan


Publication Summary


Total: ~376 peer-reviewed papers

H index: 79

Total citations:>19,500

25 papers with citation numbers of > 200 times,

and 60 papers> 100 times

Patents: 14 issued patents

2014 Publications

27.Mingxu You , Guizhi Zhu , Tao Chen , Michael Donovan , and Weihong Tan. Programmable and Multiparameter DNA-based Logic Platform For Cancer Recognition and Targeted Therapy, Journal of the American Chemical Society,(online)

26. Cuisong Zhou, Tao Chen, Cuichen Wu, Guizhi Zhu, Liping Qiu, Cheng Cui, Weijia Hou and Tan, Weihong. Aptamer-CaCO3 nanostructures: A facile, pH-responsive, specific platform for targeted anticancer theranostics, Chemistry - An Asian Journal, (online)

25. Zhu, Guizhi; Sena Cansiz; Mingxu You; Liping Qiu; Ting Fu; Da Han; Liqin Zhang; Lei Mei; Tan, Weihong. Nuclease-resistant Synthetic Drug-DNA Adducts: Programmable Drug-DNA Conjugation for Targeted Anticancer Drug Delivery, NPG Asia Materials , (accepted)

24. Song, Zhi-Ling; Bian, Xia; Zhou, Li-Yi; Ding, Ding; Liang, Hao; Zou, Yu-Xiu; Wang, Shan-Shan; Chen, Long; Yang, Chao; Zhang, Xiao-Bing; Chen, Zhuo; Tan, Weihong. Alkyne-Functionalized Superstable Graphitic Silver Nanoparticles for Raman Imaging, Journal of the American Chemical Society, 2014, 136 (39), pp 13558–13561.Full Text

23. Qiu, Liping; Zhang, Tao; Jiang, Jianhui; Wu, Cuichen; Zhu, Guizhi; You, Mingxu; Chen, Xigao; Zhang, Liqin; Cui, Cheng; Yu, Ruqin; Tan, Weihong. Cell Membrane-Anchored Biosensors for Real-Time Monitoring of the Cellular Microenvironment, Journal of the American Chemical Society, 2014, 136 (38), pp 13090–13093.Full Text

22. Liu, Yuan; Chen, Tao; Wu, Cuichen; Qiu, Liping; Hu, Rong; Li, Juan; Cansiz, Sena; Zhang, Liqin; Cui, Cheng; Zhu, Guizhi; You, Mingxu; Zhang, Tao; Tan, Weihong. Facile Surface Functionalization of Hydrophobic Magnetic Nanoparticles, Journal of the American Chemical Society, 2014, 136 (36), pp 12552–12555.Full Text

21.Zhao, Zilong; Fan, Huanhuan; Zhou, Gaofeng; Bai, Huarong; Liang, Hao; Wang, RuoWen; Zhang, Xiaobing; Tan, Weihong. Activatable fluorescence/MRI bimodal platform for tumor cell imaging via MnO2 nanosheet-aptamer nanoprobe, Journal of the American Chemical Society, 2014, 136 (32), pp 11220–11223.Full Text

20. RuoWen Wang, Chunming Wang, Cao Yang, Zhi Zhu, Chaoyong James Yang, Jianzhong Chen, Feng-Ling Qing and Weihong Tan. Trifluoromethylated Nucleic Acid Analogues Capable of Self-Assembly through Hydrophobic Interactions, Chemical Sciences 2014,5, 4076-4081.Full Text

19. Huang, Fujian; Xu, Huaguo; Tan, Weihong; Liang, Haojun. Multicolor and Erasable DNA Photolithography, ACS Nano 2014, 8 (7), pp 6849–6855. Full Text

18. Nannan Wang Zhao, Yifan Lv, Huanhuan Fan, Huarong Bai, Hongmin Meng, Yuqian Long, Ting Fu, Xiaobing Zhang and Weihong Tan. Gold nanorod-photosensitizer conjugate with extracellular pH-driven tumor targeting ability for photothermal/photodynamic therapy, Nano Research 2014, Volume 7, Issue 9, pp 1291-1301. Full Text

17. Meng, Hong-Min; Zhang, Xiaobing; Lv, Yifan; Zhao, Zilong; Wang, Nan-Nan; Fu, Ting; Fan, Huanhuan; Liang, Hao; Qiu, Liping; Zhu, Guizhi; Tan, Weihong. DNA Dendrimer: An Efficient Nanocarrier of Functional Nucleic Acids for Intracellular Molecular Sensing, ACS Nano, 2014, 8, 6171–6181). Full Text

16. Zhou, Liyi; Zhang, Xiaobing; Wang, Qianqian; Lv, Yifan; Mao, Guojiang; Luo, Aili; Wu, Yongxiang; Wu, Yuan; Zhang, Jing; Tan, Weihong. Molecular Engineering of a TBET-based Two-Photon Fluorescent Probe for Ratiometric Imaging of Living Cells and Tissues, Journal of the American Chemical Society, 2014, 136 (28), pp 9838–9841. Full Text

15. Liang, Hao; Zhang, Xiao Bing; Lv, Yifan; Gong, Liang; Wang, RuoWen; Zhu, Xiaoyan; Yang, Ronghua; Tan, Weihong. Functional DNA-containing Nanomaterials: Cellular Applications in Biosensing, Imaging and Targeted Therapy, Accounts of Chemical Research, 2014, 47, 1891–1901. Full Text

14.Hu, Rong; Liu, Tao; Zhang, Xiao Bing; Huan, Shuang-Yan; Wu, Cuichen; Fu, Ting; Tan, Weihong. Multicolor Fluorescent Biosensor for Multiplexed Detection of DNA, Analytical Chemistry 2014, 86, 5009–5016. Full Text

13. Van Simaeys, Dimitri; Turek, Diane; Champanhac, Carole; Vaizer, Julia; Sefah, Kwame; Zheng, Jing; Sutphen, Rebecca; Tan, Weihong. Identification of cell membrane protein stress-induced-phosphoprotein 1 (STIP1) as a potential ovarian cancer biomarker using aptamers selected by cell-SELEX, Analytical Chemistry 2014, 86, 4521–4527. Full Text

12. Rong Hu, Xiaobing Zhang, Zilong Zhao, Guizhi Zhu, Tao Chen, Ting Fu, Weihong Tan. DNA Nanoflowers for Multiplexed Cellular Imaging and Traceable Targeted Drug Delivery, Angewandte Chemie, International Edition 2014, 53, 5821 –5826. Full Text

11. Peng, Lu; You, Mingxu; Wu, Cuichen; Han, Da; Ocsoy, Ismail; Chen, Tao; Chen, Zhuo; Tan, Weihong. Reversible Phase Transfer of Nanoparticles Based on Photoswitchable Host-Guest Chemistry, ACS Nano, 2014, 8, 2555–2561. Full Text

10.Kwame Sefah , Zunyi Yang , Kevin M Bradley , Shuichi Hoshika , Elizabeth Jimenez , Liqin Zhang , Guizhi Zhu , Savita Shanker , Fahong Yu , Weihong Tan and Steven A. Benner,In vitro selection with artificial expanded genetic information systems, Proceedings of the National Academy of Sciences, 2014, 111, 1449. Full Text

9. RuoWen Wang, Guizhi Zhu, Lei Mei, Yan Xie, Haibin Ma, Mao Ye, Feng-Ling Qing, and Weihong Tan, Automated Modular Synthesis of Aptamer-Drug Conjugates for Targeted Drug Delivery, Journal of the American Chemical Society , 2014, 136, 2731. Full Text

8. Mingxu You, Lu Peng, Na Shao, Liqin Zhang, Liping Qiu, Cheng Cui and Weihong Tan, DNA "Nano-Claw": Logic-based Autonomous Cancer Targeting and Therapy, Journal of the American Chemical Society 2014, 136, 1256. Full Text

7. Qiaoling Liu, Jin Chen, Yanyue Wang, Xiaohong Fang, Xiaobing Zhang, Zhuo Chen and Weihong Tan, Aptamer-conjugated nanomaterials for specific cancer cell recognition and targeted cancer therapy, NPG Asia Materials 2014, 6, e95; doi:10.1038/am.2014.12 Full Text

6. Firas H. Kobeissy, Basri Gulbakan, Ali Alawieh, Pierre Karam, Zhiqun Zhang, Joy D. Guingab-Cagmat, Stefania Mondello, Weihong Tan, John Anagli and Kevin Wang, Post-Genomics Nanotechnology Is Gaining Momentum: Nanoproteomics and Applications in Life Sciences, OMICS A Journal of Integrative Biology, 2014, 18:111. Full Text

5. Chunmei Li, Tao Chen, Ismail Ocsoy, Guizhi Zhu, Emir Yasun, Mingxu You, Cuichen Wu, Jing Zheng, Erqun Song, Cheng Zhi Huang, Weihong Tan. Gold-Coated Fe3O4 Nanoroses with Five Unique Functions for Cancer Cell Targeting, Imaging and Therapy, Advanced Functional Materials 2014, 24, 1772 Full Text

4. Baosheng Guo, Baoting Zhang, Lizhen Zheng, Tao Tang, Jin Liu, Heng Wu, Zhijun Yang, Songlin Peng, Xiaojuan He, Hongqi Zhang, Kevin K.M. Yue, Fuchu He, Lingqiang Zhang, Ling Qin, Zhaoxiang Bian, Weihong Tan, Zicai Liang, Aiping Lu, Ge Zhang, Therapeutic RNA Interference Targeting CKIP-1 with a Cross-Species Sequence to Stimulate Bone Formation, Bone, 2014, 59, 76-88. Full Text

3. Weina Liu, Ding Ding, Zhuo Chen and Weihong Tan, Hollow graphitic nanocapsules as efficient electrode materials for sensitive Hydrogen peroxide detection, Biosensors & Bioelectronics, 2014, 53, 438-444. Full Text

2. Ding Ding, Zhi-Ling Song, Zhen-Qian Cheng, Wei-Na Liu, Xiang-Kun Nie, Xia Bian, Zhuo Chen, and Weihong Tan, Plasma-Assisted Nitrogen Doping of Graphene-Encapsulated Pt Nanocrystals as Efficient Fuel Cell Catalysts, Journal of Materials Chemistry, 2014, 2,472-477. Full Text

1. Fujian Huang, Mingxu You, Tao Chen, Guizhi Zhu, Haojun Liang, and Weihong Tan. Self-assembled Hybrid Nanoparticles for Targeted Co-delivery of Two Drugs into Cancer Cells, Chemical Communications, 2014,50, 3103-3105 Full Text

2013 Publications

1. Xiangling Xiong, Haipeng Liu, Zilong Zhao, Meghan B. Altman, Dalia Lopez-Colon, Lung-Ji Chang, Chen Liu, Chaoyong J. Yang and Weihong Tan, DNA Aptamer-mediated Cell Targeting, Angewandte Chemie, International Edition, 2013, 52, 1472. Full Text

2. Tao Chen, Cuichen Sam Wu, Elizabeth Jimenez, Zhi Zhu, Joshua G. Dajac, Mingxu You, Da Han, Xiaobing Zhang and Weihong Tan, DNA Micelle Flares for Intracellular mRNA Imaging and Gene Therapy, Angewandte Chemie, International Edition, 2013, 52, 2012. Full Text

3. Guizhi Zhu, Shengfeng Zhang, Erqun Song, Jing Zheng, Rong Hu, and Weihong Tan, Building Fluorescent DNA Nanodevices on Target Living Cell Surfaces, Angewandte Chemie, International Edition, 2013, 52, 5490. Full Text

4. Zilong Zhao, Hongmin Meng, Nannan Wang, Michael J. Donovan, Ting Fu, Mingxu You, Xiaobing Zhang and Weihong Tan, A Nanocarrier with pHe-driven Targeting and Translocating for Drug Delivery, Angewandte Chemie, International Edition, 2013, 52, 7487. Full Text

5. Quan Yuan, Yuan Wu, Jie Wang, Danqing Lu, Zilong Zhao, Tao Liu, Xiaobing Zhang, and Weihong Tan, Engineering a Targeted Bioimaging and Photodynamic Therapy Nanoplatform Using an Aptamer-guided G-quadruplex DNA Carrier with Near-Infrared Light, Angewandte Chemie, International Edition, 2013, 52, 13965. Full Text

6. Guizhi Zhu, Jing Zheng, Erqun Song, Michael Donovan, Kejing Zhang, Chen Liu and Weihong Tan, Self-assembled, Aptamer-tethered DNA Nanotrains for Targeted Transport of Molecular Drugs in Cancer Theranostics, Proceedings of the National Academy of Sciences USA, 2013, 110, 7998-8003. Full Text

7. Fujian Huang, Mingxu You, Da Han, Xiangling Xiong, Haojun Liang and Weihong Tan, DNA Branch Migration Reactions Through Photocontrollable Toehold Formation, Journal of the American Chemical Society, 2013, 135, 7967-7973. Full Text

8. Liping Qiu, Cuichen Wu, Mingxu You, Da Han, Tao Chen, Guizhi Zhu, Jianhui Jiang, Ruqin Yu and Weihong Tan, A Targeted, Self-delivered and Photocontrolled Molecular Beacon for Spatiotemporal mRNA Detection in Living Cells, Journal of the American Chemical Society, 2013, 135, 12952. Full Text

9. Guizhi Zhu, Rong Hu, Zilong Zhao, Zhuo Chen, Xiaobing Zhang and Weihong Tan, Noncanonical self-assembly of multifunctional DNA nanoflowers for biomedical applications, Journal of the American Chemical Society, 2013, 135, 16438-16445. Full Text

10. Cuichen Wu, Da Han, Tao Chen, Lu Peng, Guizhi Zhu, Mingxu You, Liping Qiu, Kwame Sefah, and Weihong Tan, Building a Multifunctional Aptamer-Based DNA Nanoassembly for Targeted Cancer Therapy, Journal of the American Chemical Society, 2013, 135,18644–18650. Full Text

11. Meghan B. Altman, Yun Min Chang, Xiangling Xiong, and Weihong Tan, Modifying cellular properties using artificial aptamer-lipid receptors, Scientific Reports, 2013, 3, 3343. Full Text

12. Ismail Ocsoy, Basri Gulbakan, Tao Chen, Guizhi Zhu, Zhuo Chen, Mufrettin Murat Sari, Lu Peng, Xiangling Xiong and Weihong Tan, DNA-Guided-Metal Nanoparticle Formation on Graphene Oxide Surface, Advanced Materals, 2013, 25, 2319-2325. Full Text

13. Weihong Tan, Michael J. Donovan and Jianhui Jiang, Aptamers from Cell-Based Selection for Bioanalytical Applications, Chemical Reviews, 2013, 113, 4, 2842-2862. Full Text

14. Chaoyong James Yang and Weihong Tan, Eds., Molecular Beacons, Springer, 2013, 254 pp.

15. Kwame Sefah, Kyung-Mi Bae, Joseph A. Phillips, Dietmar W. Siemann, Zhen Su, Steve McClellan, Johannes Vieweg and Weihong Tan, Cell-based selection provides novel molecular probes for cancer stem cells, International Journal of Cancer, 2013, 132, 2578-2588. Full Text

16. Hui Wang, Michael J. Donovan, Ling Meng, Zilong Zhao, Youngmi Kim, Mao Ye and Weihong Tan, DNAzyme-Based Probes for Telomerase Study in Early-Stage Cancer Detection, Chemistry A European Journal, 2013, 19, 4633. Full Text

17. Cuichen Sam Wu, Tao Chen, Da Han, Mingxu You, Lu Peng, Sena Cansiz, Guizhi Zhu, Chunmei Li, Xiangling Xiong, Chaoyong James Yang, Weihong Tan, Engineering of Switchable Aptamer Micelle Flares for Molecular Imaging in Living Cells, ACS Nano, 2013, 7, 5724-5731. Full Text

18. Ismail Ocsoy, Basri Gulbakan, M. Ibrahim Shukoor, X. Xiong, D. H. Powell and Weihong Tan, Aptamer conjugated multifunctional nanoflowers as a novel platform for targeting, capture and detection in laser desorption ionization mass spectrometry, ACS Nano, 2013, 7, 417-427. Full Text

19. Da Han, Guizhi Zhu, Cuichen Sam Wu, Zhi Zhu, Xiaobing Zhang and Weihong Tan, Engineering a cell-surface aptamer circuit for targeted and amplified photodynamic cancer therapy, ACS Nano, 2013, 7, 2312-2319. Full Text

20. Jing Zheng, Guizhi Zhu, Yinhui Li, Chunmei Li, Mingxu You, Tao Chen, Erqun Song, Ronghua Yang and Weihong Tan, A Multifunctional Spherical Nucleic Acid-Conjugate Platform Based on Self-Assembled DNA Biopolymer for Cancer Therapy, ACS Nano, 2013, 7, 6545-6554. Full Text

21. Weian Sheng, Tao Chen, Weihong Tan, and Z. Hugh Fan, Multivalent DNA Nanospheres for Enhanced Capture of Cancer Cells in Microfluidic Devices, ACS Nano, 2013, 7, 7067-7076. Full Text

22. Ismail Ocsoy, Mathews L. Paret, Muserref Arslan Ocsoy, Sanju Kunwar Tao Chen, Mingxu You and Weihong Tan, Nanotechnology in Plant Disease Management: DNA-directed Silver Nanoparticles on Graphene Oxide as an Antibacterial against Xanthomonas Perforans, ACS Nano, 2013, 7, 8972-8980. Full Text

23. Jinhua Liu, Changyao Wang, Ying Jiang, Yaping Hu, Jishan Li, Sheng Yang, Yinhui Li, Ronghua Yang and Weihong Tan and Chengzhi Huang Graphene Signal Amplification for Sensitive and Real-Time Fluorescence Anisotropy Detection of Small Molecule, Analytical Chemistry, 2013, 85, 1424-1430. Full Text

24. Xu-Hua Zhao, Liang Gong, Xiao-Bing Zhang, Ting Fu, Rong Hu, Weihong Tan and Ruqin Yu, Versatile DNAzyme-based Amplified Biosensing Platformsfor Nucleic Acid, Protein and Enzyme Activity Detection, Analytical Chemistry, 2013, 85, 3614-3620. Full Text

25. Li Deng, X. Ouyang, Jianyu Jin, Cheng Ma, Ying Jiang, Jing Zheng, Jishan Li, Yinhui Li, Weihong Tan and Ronghua Yang, Exploiting the Higher Specificity of Silver Amalgamation: Selective Detection of Mercury (II) by Forming Ag/Hg Amalgam, Analytical Chemistry, 2013, 85, 8594. Full Text

26. Guo-Jiang Mao, Tian-Tian Wei, Xu-Xiang Wang, shuangyan Huan, Danqing Lu, Jing Zhang, XiaoBing Zhang, Weihong Tan, Guo-Li Shen, and Ruqin Yu, A Highly Sensitive Naphthalene-based Two-Photon Fluorescent Probe Suitable for Direct Bio-imaging of H2S in Living Cells, Analytical Chemistry, 2013, 85, 7875-7881. Full Text

27. Bin Yang, Xiao-Bing Zhang, Li-Ping Kang, Guo-Li Shen, Ru-Qin Yu, and Weihong Tan, Target-Triggered Cyclic Assembly of DNA-Protein Hybrid Nanowires for Dual-Amplified Fluorescence Anisotropy Assay of Small Molecules, Analytical Chemistry, 2013, 85. Full Text

28. Zhi-Ling Song, Xu-Hua Zhao, Wei-Na Liu, Ding Ding, Xia Bian, Hao Liang, Xiao-Bing Zhang, Zhuo Chen and Weihong Tan, Magnetic Graphitic Nanocapsules for Programmed DNA Fishing and Detection, Small, 2013, 9, 951-957. Full Text

29. Jian Wang, Mingxu You, Guizhi Zhu, Mohammed Ibrahim Shukoor, Chunmei Li, Zhuo Chen, Zilong Zhao, Meghan B Altman, Quan Yuan, Zhi Zhu, Yan Chen, Cheng Zhi Huang and Weihong Tan, Photosensitizer-Gold Nanorods Composite for Targeted Multimodal Therapy, Small, 2013, 9, 378. Full Text

30. Lele Li, Mengying Xie, Jie Wang, Xinyang Li, Cheng Wang, Quan Yuan,Dai-Wen Pang, Yi Lu, and Weihong Tan, Vitamin-responsive Mesoporous Nanocarrier with DNA Aptamer-mediated Cell Targeting, Chem. Commun., 2013, 49, 5923-5. Full Text

31. Jishan Li, Yuhua Jia, Jing Zheng, Wenwan Zhong, Guoli Shen, Ronghua Yang and Weihong Tan, Aptamer Degradation Inhibiting Combined with DNAzyme Cascade-Based Signal Amplification for Colorimetric Detection of Protein, Chem. Commun., 2013, 49, 6137-9. Full Text

32. Ting Fu, XuHua Zhao, Huarong Bai, Zilong Zhao, Rong Hu, Rongmei Kong, Xiaobing Zhang, Weihong Tan and Ruqin Yu, Superquenched DNAzyme-perylene complex: a convenient, universal and low-background strategy for fluorescence catalytic biosensors, Chem. Commun., 2013, 49, 6644-6646. Full Text

33. Jiani Zhang, Bo Liu, Huixia Liu, Xiaobing Zhang and Weihong Tan, Aptamer-conjugated gold nanoparticles for biological analysis, Nanomedicine (Lond), 2013, 8, 983-993.

34. Zhonghui. H. Fan and Weihong Tan, DNA nanospheres with microfluidics: a promising platform for cancer diagnosis? Nanomedicine (Lond). 2013, 8(11):1731-3.

35. Jennifer A. Martin, Parag Parekh, Youngmi Kim, Timothy E. Morey, Kwame Sefah, Nikolaus Gravenstein, Donn M. Dennis and Weihong Tan, Selection of an Aptamer Antidote to the Anticoagulant Drug Bivalirudin, PLOS One, 2013, 8 (3) e57341. Full Text

36. Lu Peng, Cuichen Wu, Mingxu You, Da Han, Yan Chen, Ting Fu, Mao Ye and Weihong Tan, Engineering and Applications of DNA-Grafting Polymer Materials, Chemical Sciences, 2013, 4, 1928-1938. Full Text

37. Rong Hu, Ya-Ru Liu, Xiao-Bing Zhang, Weihong Tan, Guo-Li Shen and Ru-QinYu, An efficient fluorescent sensing platform for biomolecules based on fenton reaction triggered molecular beacon cleavage strategy, Biosensors & Bioelectronics, 2013, 41, 442-5. Full Text

38. Limin Lu, XL Qiu, Xiao-Bing Zhang, Weihong Tan and Ru-QinYu, Supramolecular assembly of enzyme on functionalized graphene for electrochemical biosensing, Biosensors & Bioelectronics, 2013, 45, 102-107. Full Text

39. Rong Hu, Ya-Ru Liu, Rong-Mei Kong, Michael J. Donovan, Xiao-Bing Zhang, Weihong Tan, Guo-Li Shen, Ru-QinYu, Double-strand DNA-templated formation of copper nanoparticles as fluorescent probe for label free nuclease enzymedetection, Biosensors & Bioelectronics, 2013, 42, 31-35. Full Text

40. Yang, Bing, Zhang, Xiaobing, Liu WN, Hu Rong, Tan Weihong, Shen Guoli, Yu Ruqin, Fluorosurfactant-capped gold nanoparticles-based label-free colorimetric assay for Au3+ with tunable dynamic range via a redox strategy, Biosensors & Bioelectronics, 2013, 48, 1-5. Full Text

41. Ying Pu, Huixia Liu, Bo Liu, Zilong Zhao and Weihong Tan, Development of aptamer-based nanomaterials for bioanalysis, Current Molecular Medicine, 2013, 13, 4, 681-689.

42. Amrita B. Mullick, Yun Min Chang, Ion Ghiviriga, Khalil, A. Abboud, Weihong Tan and Adam S. Veige, Human cancerous and healthy cell cytotoxicity studies of a chiral µ-dicarbene-digold(I) metallamacrocycle, Dalton Transactions, 2013, 42, 7440-7446. Full Text

43. Yun Min Chang, Michael Donovan and Weihong Tan, Using Aptamers for Cancer Biomarker Discovery, Journal of Nucleic Acids, 2013, 817350. Full Text

44. Jian Wang, Kwame Sefah, Meghan B. Altman, Tao Chen, Mingxu You, Zilong Zhao, Cheng Zhi Huang and Weihong Tan, Aptamer-Conjugated Nanorods for Targeted Photothermal Therapy of Prostate Cancer Stem Cells, Chemistry, An Asia Journal, 2013, 8, 2417. Full Text

45. Xuejie Zhang, Qiaoling Liu, Tie Xia, Nan Li, Kangmin He, Chunru Wang, Weihong Tan and Xiaohong Fang, Atomic Force Microscopy Study of the Effects of Water-Soluble Fullerenes on the Elasticity of Living Plant Cells, Chemistry, An Asia Journal, 2013, 8, Full Text

46. Changbei Ma, Zhiwen Tang, Kemin Wang, Xiaohai Yang and Weihong Tan, A novel sensitive and selective ligation-based ATP assay using a molecular beacon, Analyst, 2013, 138, 3013-3017. Full Text

47. Xiangling Xiong, Cuichen Wu, Cuisong Zhou, Guizhi Zhu, Zhuo Chen and Weihong Tan, Responsive DNA-based hydrogels and their applications, Macromol Rapid Commun., 2013, 34, 1271-1283. Full Text


Major Publications from 2001-2012

Han, Da; Zhu, Zhi; Wu, Cuichen; Peng, Lu; Zhou, Leiji; Gulbakan, Basri; Zhu, Guizhi; Williams, Kathryn; Tan, Weihong, A logical molecular circuit for programmable and autonomous regulation of protein activity using DNA aptamer-protein interactions, Journal of the American Chemical Society, 2012, 134, 20797–20804. Full Text

Jing Zheng, Anli Jiao, Jishan Li, Muling Shi, Cheng Ma, Ying Jiang, Li Deng, Huimin Li, Ronghua Yang and Weihong Tan, Fabricating Reversible and Regenerable Raman Hot Spots through Biomolecular Interaction, Journal of the American Chemical Society, 2012, 134, 19957–19960. Full Text

Mingxu You, Yan Chen, Xiaobing Zhang, Haipeng Liu, Ruowen Wang, Kelong Wang, Kathryn R. Williams and Weihong Tan, An Autonomous and Controllable Light-Driven DNA Walking Device, Angewandte Chemie, International Edition, 2012, 51, 2457-2460. Full Text

Lu Peng, Mingxu You, Quan Yuan, Cuichen Wu, Da Han, Yan Chen, Zhihua Zhong, Jiangeng Xue and Weihong Tan, Macroscopic Volume Change of Dynamic Hydrogels induced by Reversible DNA Hybridization, Journal of the American Chemical Society, 2012, 134, 12302-12307. Full Text

Tao Chen, Ismail Ösçoy, Q. Yuan, R. Wang, Mingxu You, Z. Zhao, Erqun Song, Xiaobing Zhang and Weihong Tan, One-Step Facile Surface Engineering of Hydrophobic Nanocrystals with Designer Molecular Recognition, Journal of the American Chemical Society, 2012, 134, 13164-13167.Full Text

Bincheng Yin, Mingxu You, Weihong Tan and Bangce Ye, Mercury(II) Ions Detection via Pyrene-Mediated Photolysis of Disulfide Bonds, Chemistry - A European Journal, 2012, 18 (5)1286-1289. Full Text

Suwussa Bamrungsap, Tao Chen, Mohammed Ibrahim Shukoor, Zhuo Chen, Michael J. Donovan, Kwame Sefah, Yan Chen, and Weihong Tan, Pattern Recognition of Cancer Cells Using Aptamer-Conjugated Magnetic Nanoparticles, ACS Nano, 2012, 6, 3974-3981. Full Text

Jian Wang, Guizhi Zhu, Mingxu You, Meghan B. O'Donoghue, Mohammed Ibrahim Shukoor, Kejing Zhang, Yan Chen, Zhi Zhu, Erqun Song, Cheng Zhi Huang and Weihong Tan, Assembly of Aptamer Switch Probes and Photosensitizer on Gold Nanorods for Targeted Photothermal and Photodynamic Cancer Therapy, ACS Nano, 2012, 6, 5070-5077. Full Text

Yuan, Quan; Zhang, Yunfei; Chen, Tao; Lu, Danqing; Zhao, Zilong; Zhang, Xiaobing; Li, Z.; Yan, Chun-Hua; Tan, Weihong, Photon-manipulated Drug Release from a Mesoporous Nanocontainer Controlled by Azobenzene-modified Nucleic Acid, ACS Nano, 2012, 6, 6337-6344.Full Text

Mingxu You, Fujian Huang, Zhuo Chen, Ruo-Wen Wang, and Weihong Tan, Building a Nanostructure with Reversible Motions Using Photonic Energy, ACS Nano, 2012, 6, 7935-7941. Full Text

Quan Yuan, Yunfei Zhang, Yan Chen, Ruowen Wang, Chaolin Du, Emir Yasun, Weihong Tan, Using Silver Nanowire Antennas to Enhance the Conversion Efficiency of Photoresponsive DNA Nanomotors, Proceedings of the National Academy of Sciences, 2011, 108, 9331-9336. Full Text

Kelong Wang, Mingxu You, Yan Chen, Da Han, Zhi Zhu, Jin Huang, Kathryn Williams, Chaoyong James Yang and Weihong Tan, Self-assembly of a Bifunctional DNA Carrier for Drug Delivery,Angewandte Chemie, International Edition, 2011, 50, 6114.Full Text

Liu Yang, Ling Meng, Yan Chen, Xiaoibing Zhang, Guizhi Zhu, Haipeng Liu, Kwame Sefah, Zhi Zhu and Weihong Tan, Engineering Polymeric Aptamers for Selective Cytotoxicity, Journal of the American Chemical Society, 2011, 133, 13380–13386 Full Text

Jin Huang, Yanrong Wu, Yan Chen, Zhi Zhu, Xiaohai Yang, Chaoyong James Yang, Kemin Wang and Weihong Tan, Pyrene Excimer Probes for Nucleic Acids in Complex Biological Fluids Based on Hybridization Chain Reaction Amplification, Angewandte Chemie, International Edition, 2011, 50, 401. Full Text

Hui Shi, Xiaoxiao He, Kemin Wang, Xu Wu, Xiaosheng Ye, Qiuping Guo, Weihong Tan, Zhihe Qing, Xiaohai Yang, and Bing Zhou, An Activatable Aptamer Probe for Contrast-Enhanced in Vivo Cancer Imaging Based on Cell Membrane Protein-Triggered Conformation Alteration, Proceedings of the National Academy of Sciences of the United States of America, 2011, 108, 3900-3905. Full Text

Weihong Tan, Hui Wang, Yan Chen, Xiaobing Zhang, Haizhen Zhu, Chaoyong Yang, Ronghua Yang and Chen Liu, Molecular aptamers for drug delivery, Trends in Biotechnology (Cell Press), 2011, 29, 634-640. Full Text

Li-Min Lu, Xiao-Bing Zhang, Rong-Mei Kong, Bin Yang, Weihong Tan, A Ligation-triggered DNAzyme Cascade for Amplified Fluorescence Detection of Biological Small Molecules with Zero-Background Signal, Journal of the American Chemical Society, 2011, 133, 11686-11691. Full Text

Huaizhi Kang, Anna Carolina Trondoli, Guizhi Zhu, Yan Chen, Ya-Jen Chang, Haipeng Liu, Yu-Fen Huang, Xiaoling Zhang and Weihong Tan, Near-Infrared Light-Responsive Core-Shell Nanogels for Targeted Drug Delivery, ACS Nano, 2011, 5, 5094–5099. Full Text

Tao Chen, Mohammed I. Shukoor, Ruowen Wang, Zilong Zhao, Quan Yuan, Suwussa Bamrungsap, Xiangling Xiong, Weihong Tan, Smart Multifunctional Nanostructure for Targeted Cancer Chemotherapy and Magnetic Resonance Imaging, ACS Nano, 2011, 5, 7866-7873. Full Text

Zhan Wu, Li-Juan Tang, Xiao-Bing Zhang, Jian-Hui Jiang, and Weihong Tan, Aptamer-Modified Nanodrug Delivery Systems, ACS Nano, 2011, 5, 7696–7699. Full Text

Mingxu You,Ruo-Wen Wang, Xiaobing Zhang, Yan Chen, Kelong Wang, Lu Peng and Weihong Tan, Photon-Regulated DNA-Enzymatic Nanostructures by Molecular Assembly, ACS Nano, 2011, 5, 10090-10095. Full Text

Suwussa Bamrungsap, Joseph A. Phillips, Xiangling Xiong, Youngmi Kim, Hui Wang, Haipeng Liu, Arthur Hebard, and Weihong Tan, Magnetically Driven Single DNA Nanomotor, Small, 2011, 7, 601.Full Text

Yanrong Wu, Kwame Sefah, Haipeng Liu, Ruowen Wang, and Weihong Tan, DNA Aptamer-Micelle as an Efficient Detection /Delivery Vehicle toward Cancer Cells, Proceedings of the National Academy of Sciences of the United States of American, 2010, 107, 5-10. Full Text

Kwame Sefah, Dihua Shangguan Xiangling Xiong, Meghan B. O'Donoghue and Weihong Tan, Development of DNA aptamers using the Cell-SELEX strategy, Nature Protocol, 2010, 5 (6), 1169-1185. Full Text

Xiaohong Fang and Weihong Tan, Aptamers Generated from Cell-SELEX for Molecular Medicine: A Chemical Biology Approach, Accounts of Chemical Research , 2010, 43(1), 48-57. Full Text

Yan Chen, Meghan B. O'Donoghue, Yu-Fen Huang, Huaizhi Kang, Joseph A. Phillips, Xiaolan Chen, M.-Carmen Estevez, Chaoyong J. Yang and Weihong Tan, A Surface Energy Transfer Nanoruler for Measuring Binding Site Distances on Live Cell Surfaces, Journal of American Chemical Society, 2010, 132, 16559–16570. Full Text

Zhi Zhu, Cuichen Wu, Haipeng Liu, Yuan Zou, Xiaoling Zhang, Huaizhi Kang, Chaoyong James Yang and Weihong Tan, DNA Aptamer-Crosslinked Hydrogel As a Colorimetric Platform For Visual Detection, Angewandte Chemie, International Edition, 2010, 49, 1052. Full Text

Basri Gulbakan, Emir Yasun, M. Ibrahim Shukoor, Zhi Zhu, Mingxu You, Xiaohong Tan, Hernan Sanchez, D. Powell, Hongjie Dai and Weihong Tan, A dual platform for selective analyte enrichment and ionization in mass spectrometry using aptamer-conjugated graphene oxide, Journal of American Chemical Society, 2010, 32 (49), pp 17408–17410. Full Text

Youngmi Kim, Joseph A. Phillips, Haipeng Liu, Huaizhi Kang and Weihong Tan, Using photons to manipulate enzyme inhibition by an azobenzene-modified nucleic acid probe,Proceedings of the National Academy of Sciences of the United States of America,, 2009, 106: 6489-6494. Full Text

Hui Wang, Youngmi Kim, H. Liu, Z. Zhu, S. Bamrungsap and Weihong Tan, Engineering a unimolecular DNA-catalytic probe for single lead ion monitoring, Journal of American Chemical Society, 2009, 131, 8221-8226. Full Text

Huaizhi Kang, Haipeng Liu, Joseph A. Phillips, Zehui Cao, Youngmi Kim, Yan Chen, Zunyi Yang, Jianwei Li and Weihong Tan, A Single-DNA Molecule Nanomotor Regulated by Photons, Nano Letters, 2009, 9, 2690. Full Text

Kwame Sefah, Zhiwen Tang, Dihua Shangguan, Hui Chen, Dalia Lopez-Colon, Ying Li, Parag Parekh, Jennifer Martin, Ling Meng and Joseph A. Phillips, Y. Kim and Weihong Tan, Molecular Recognition of Acute Myeloid Leukemia Using Aptamers, Nature Leukemia, 2009, 23, 235–244. Full Text

Kemin Wang, Zhiwen Tang, Chaoyong Yang, Youngmi Kim, X Fang, Yanrong Wu, Wei Li, Jun Li, Colin Medley, Zehui Cao, Patrick Colon, Hui Lin and Weihong Tan, Molecular engineering of DNA: molecular beacons, Angewandte Chemie, International Edition, 2009, 48, 856-870. Full Text

Bin-Cheng Yin, Bang-Ce Ye, Weihong Tan, Hui Wang and Cong-Cong Xie, An Allosteric Dual-DNAzyme Unimolecular Probe for Colorimetric Detection of Copper(II), Journal of American Chemical Society. 2009, 131, 14624. Full Text

Yu-Fen Huang, Haipeng Liu, Xiangling Xiong, Yan Chen and Weihong Tan, Nanoparticle-mediated IgE-Receptor Aggregation and Signaling in RBL Mast Cells, Journal of American Chemical Society, 2009, 131, 17328-17334.Full Text

Youngmi Kim, Zehui Cao, and Weihong Tan, Molecular assembly for high performance bivalent nucleic acid inhibitor, Proceedings of the National Academy of Sciences of the United States of American,, 2008, 105, 5664-5669. Full Text

Tang, Zhiwen; Mallikaratchy, Prabodhika; Yang, Ronghua; Kim, Youngmi; Zhu, Zhi; Wang, Hui; Tan, Weihong. Aptamer Switch Probe Based on Intramolecular Displacement, Journal of American Chemical Society. (2008), 130, 11268-11269. Full Text

Patrick Conlon, C. J. Yang, Y. Wu, Yan Chen, Karen Martinez, Y. Kim, Nathan Stevens, A. Marti, Steffen Jockusch, Nicholas J. Turro, Weihong Tan, Pyrene Excimer Signaling Molecular Beacons for Probing Nucleic Acids, Journal of the American Chemical Society, 2008, 130, 336-342. Full Text

Zhu, Zhi; Tang, Zhiwen; Phillips, Joseph A.; Yang, R., Wang, Hui; Tan, Weihong. Regulation of Singlet Oxygen Generation Using Single-Walled Carbon Nanotubes, Journal of the American Chemical Society (2008), 130, 10856-10857. Full Text

Yang, Ronghua; Jin, Jianyu; Chen, Yan; Shao, Na; Kang, Huaizhi; Xiao, Zeyu; Tang, Zhiwen; Wu, Yanrong; Zhu, Zhi; Tan, Weihong, Carbon Nanotube-Quenched Fluorescent Oligonucleotides: Probes that Fluoresce upon Hybridization, Journal of the American Chemical Society (2008), 130(26), 8351-8358. Full Text

Yang, Huanghao; Liu, Haipeng; Kang, Huaizhi; Tan, Weihong, Engineering Target-Responsive Hydrogels Based on Aptamer-Target Interactions, Journal of the American Chemical Society (2008), 130, 6320-6321. Full Text

Dihua Shuangguan, Zehui Cao, Ling Meng, P. Mallikaratchy, K. Sefah, Hui Wang, Ying Li and Weihong Tan, Cell-specific aptamer probes for membrane protein elucidation in cancer cells, Journal of Proteome Research, 2008, 7, 2133-2139. Full Text

Prabodhika Mallikaratchy, Zhiwen Tang, Ling Meng, Dihua Shangguan, Sefah Kwame and Weihong Tan, Aptamer directly evolved from live cells recognizes membrane bound immunoglobin heavy mu chain in Burkitt's Lymphoma cells, Molecular and Cellular Proteomics, 2007, 6 (12), 2230-2238.Full Text

Xing, Hong; Chen, Meng; Ling, Jennifer; Tan, Weihong; Gu, Jianguo G. TRPM8 mechanism of cold allodynia after chronic nerve injury, Journal of Neuroscience, 2007, 27(50), 13680-13690.Full Text

Shangguan, Dihua; Li, Ying; Tang, Zhiwen; Cao, Zehui Charles; Chen, H; Mallikaratchy, Prabodhika; Sefah, Kwame; Yang, Chaoyong James; Tan, Weihong, Aptamers evolved from live cells as effective molecular probes for cancer study, Proceedings of the National Academy of Sciences of the United States of America, 2006, 103, 11838-11843. Full Text

Yang, Chaoyong James; Martinez, Karen; Lin, Hui; Tan, Weihong, Hybrid Molecular Probe for Nucleic Acid Analysis in Biological Samples. Journal of the American Chemical Society, 2006, 128, 9986-9987. Full Text

Wang, Lin; Tan, Weihong, Multicolor FRET Silica Nanoparticles by Single Wavelength Excitation, Nano Letters, 2006, 6(1), 84. Full Text

Yang, Chaoyong James; Jockusch, Steffen; Vicens, Marie; Turro, Nicholas J.; Tan, Weihong, Light-switching excimer probes for rapid protein monitoring in complex biological fluids, Proceedings of the National Academy of Sciences of the United States of America, 2005, 102, 17278-83. Full Text

Wang, Lin; Yang, Chaoyong James; Medley, Colin D.; Benner, Steven A.; Tan, Weihong Locked Nucleic Acid Molecular Beacons. Journal of the American Chemical Society, 2005, 127(45), 15664-15665.Full Text

Yang, Chaoyong James; Lin, Hui; Tan, Weihong, Molecular Assembly of Superquenchers in Signaling Molecular Interactions, Journal of the American Chemical Society, 2005, 127(37), 12772-12773. Full Text

Yang, Chaoyong James; Pinto, Mauricio; Schanze, Kirk S.; Tan, Weihong, Direct synthesis of an oligonucleotide-poly(phenylene ethynylene) conjugate with a precise one-to-one molecular ratio, Angewandte Chemie, International Edition, 2005, 44(17), 2572.Full Text

Wang, Lin; Yang, CJ; Tan, Weihong, Dual-luminophore-doped silica nanoparticles for multiplexed signaling, Nano Letters, 2005, 5, 37-43. Full Text

Zhao, Xiaojun; Hilliard, Lisa R.; Mechery, Shelly John; Wang, Yanping; Bagwe, Rahul P.; Jin, Shouguang; Tan, Weihong, A rapid bioassay for single bacterial cell quantitation using bioconjugated nanoparticles, Proceedings of the National Academy of Sciences of the United States of America, 2004, 101(42), 15027-15032. Full Text

Kohli, Punit; Harrell, C. Chad; Cao, Zehui; Gasparac, Rahela; Tan, Weihong; Martin, Charles R., DNA-Functionalized Nanotube Membranes with Single-Base Mismatch Selectivity, Science, 2004, 305(5686), 984-986. Full Text

Zhao, Xiaojun; Tapec-Dytioco, Rovelyn; Tan, Weihong. Ultrasensitive DNA detection using highly fluorescent bioconjugated nanoparticles. Journal of the American Chemical Society (2003), 125(38), 11474-11475. Full Text

He, Xiao-Xiao; Wang, Kemin; Tan, Weihong; Liu, Bin; Lin, Xia; He, Chunmei; Li, Du; Huang, Shasheng; Li, Jun. Bioconjugated nanoparticles for DNA protection from cleavage. Journal of the American Chemical Society (2003), 125(24), 7168-7169. Full Text

Li, Jianwei J.; Tan, Weihong. A single DNA molecule nanomotor. Nano Letters (2002), 2(4), 315-318. Full Text

Santra, Swadeshmukul; Zhang, Peng; Wang, Kemin; Tapec, Rovelyn; Tan, Weihong. Conjugation of Biomolecules with Luminophore-Doped Silica Nanoparticles for Photostable Biomarkers, Analytical Chemistry (2001), 73(20), 4988-4993. Full Text

Santra, Swadeshmukul; Tapec, Rovelyn; Theodoropoulou, Nikoleta; Dobson, Jon; Hebard, Arthur; Tan, Weihong, Synthesis and Characterization of Silica-Coated Iron Oxide Nanoparticles in Microemulsion: The Effect of Nonionic Surfactants. Langmuir (2001), 17(10), 2900-2906. Full Text

Zhang, Peng; Beck, Terry; Tan, Weihong. Design of a molecular beacon DNA probe with two fluorophores. Angewandte Chemie, International Edition (2001), 40(2), 402-405. Full Text


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