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Hi, Welcome to our Website!

Dr. Weihong Tan, the V. T. and Louise Jackson Professor of Chemistry at the University of Florida, is our principal investigator and well recognized for work in chemical biology, molecular engineering, and bionanotechnology. Tan's group has more than 25 students, postdoctors and research scientists working on three major areas:

Molecular Engineering: synthesizing novel molecular probes for bioanalysis, biosensors, biomedical applications;
Bionanotechnology: making new tools for enhanced biomedical studies using nanotechnology and nanomaterials;

Chemical Biology: understanding the molecular foundation of diseases using molecular aptamers.

Enjoy your visit here.

 

Most Recent Publications in 2009:



Using aptamers evolved from cell-SELEX to engineer a molecular delivery platform. Mallikaratchy P, Liu H, Huang YF, Wang H, Lopez-Colon D, Tan W. Chem Commun (Camb). 7;(21):3056-8 (2009). Abstract.

Engineering a Unimolecular DNA-Catalytic Probe for Single Lead Ion Monitoring. Wang H, Kim Y, Liu H, Zhu Z, Bamrungsap S, Tan W. J Am Chem Soc. May 20, 2009 (Epub, ahead of Publication). Abstract

Ultra-small water-dispersible fluorescent chitosan nanoparticles: synthesis, characterization and specific targeting. Tallury P, Kar S, Bamrungsap S, Huang YF, Tan W, Santra S. Chem Commun (Camb). (17):2347-9 (2009). Abstract.

Mapping Receptor Density on Live Cells by Using Fluorescence Correlation Spectroscopy. Chen Y, Munteanu AC, Huang YF, Phillips J, Zhu Z, Mavros M, Tan W. Chemistry. 15(21):5327-36 (2009). Abstract.

Reversible molecular switching of molecular beacon: controlling DNA hybridization kinetics and thermodynamics using mercury(ii) ions. Yang R, Jin J, Long L, Wang Y, Wang H, Tan W. Chem Commun (Camb). 3:322-4 (2009). Abstract.

Fluorescent assay of DNA hybridization with label-free molecular switch: reducing background-signal and improving specificity by using carbon nanotubes. Liu Y, Wang Y, Jin J, Wang H, Yang R, Tan W. Chem Commun (Camb). 6:665-7 (2009). Abstract.

Enrichment of cancer cells using aptamers immobilized on a microfluidic channel. Phillips JA, Xu Y, Xia Z, Fan ZH, Tan W. Analytical Chemistry. 81(3):1033-9 (2009). Abstract.

Molecular assembly of an aptamer-drug conjugate for targeted drug delivery to tumor cells. Huang YF, Shangguan D, Liu H, Phillips JA, Zhang X, Chen Y, Tan W. Chembiochem. 10(5):862-8 (2009). Abstract.

Generating aptamers for recognition of virus-infected cells. Tang Z, Parekh P, Turner P, Moyer RW, Tan W. Clinical Chemistry. 55(4):813-22 (2009). Abstract.

Aptamers generated by Cell SELEX for biomarker discovery.
Youngmi Kim, Chen Liu, Weihong Tan. Biomarkers in Medicine. 3(2):193-202 (2009). Abstract.

Preparation and characterization of CdSe nanoparticles in the presence of Triocytlphosphine as solvent and capping agent. Shutang Chen, Xiaoling Zhang, Yanbing Zhao, Jilin Yan, Weihong Tan. Materials Letters. 63:712–714 (2009). Abstract.

Molecular Assembly of an Aptamer-Drug Conjugate for Targeted Drug Delivery to Tumor Cells. Yu-Fen Huang, Dihua Shangguan, Haipeng Liu, Joseph A. Phillips, Xiaoling Zhang, Yan Chen, Weihong Tan. ChemBioChem epub (2009). Abstract.

Molecular recognition of acute myeloid leukemia using aptamers. Sefah K, Tang ZW, Shangguan DH, Chen H, Lopez-Colon D, Li Y, Parekh P, Martin J, Meng L, Phillips JA, Kim YM, Tan WH. Leukemia. 23(2):235-44 (2009). Abstract.

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 Recent Recognition of our Work (More News):

Congratulations to Kwame Sefah for winning the 2009-2010 Ruegamer Award for Biochemistry!

Judy Zhi Zhu won a coveted ACS Graduate Student Fellowship for 2009, which covers 9 months of work. There are only three fellowships awarded nationally each year.

Congratulations to Dalia Colon Lopez for recieving an Institutional T32 Cancer Training Grant to fund her graduate work for the next two years from the National Cancer Institute. Dr. Joe Phillips also recieved one this year.

Wired Science reports on our work in the article "Glowing DNA that Sticks to Cancer Cells."

Youngmi Kim won the 2008 Herbert A. and Marjorie G. Laitinen Graduate Fellowship for the third year in a row. This award is given to the best overall graduate students in their graduate studies.

A Hot Article Alert appeared in ChemComm about our improved molecular beacon using an artifical alphabet.

Karen Martinez and Dalia Colon both won NIH Graduate Student fellowships in 2008 which covered the cost of their work for one year.

Dr. Weihong Tan was named the V. T. and Louis Jackson Professor of Chemistry.

Three recent papers using aptamers and nanoparticles were among the Top Ten most accessed articles in Analytical Chemistry for 2008.


Last Updated on Tuesday, May 26th, 2009. Site maintained by Meghan B. O'Donoghue
 The Tan Group. Chemistry Department, University of Florida.