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UF Department of Chemistry
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Hi,
Welcome to our website!
Dr.
Weihong Tan, (Dr.
Tan's CV) of the Department of Chemistry and
Shands Cancer Center at the University of Florida, is the principal
investigator and well recognized for his work in chemical biology,
molecular engineering, and bionanotechnology. Tan's group has
more than 25 students, postdoctors and research scientists and
is working on three major areas:
Molecular
Engineering: synthesizing novel molecular probes for
bioanalysis, biosensors, biotechnological and biomedical applications;
Bionanotechnology:
understanding and making use of biological phenomena on the nanometer
scale; making new tools and materials for enhanced biomedical
studies using nanotechnology and nanomaterials;
Biomedical Studies: neurogenomics
to understand memory and learning processes (gene expression monitoring
during memory formation and learning process) and molecular foundation
of diseases using molecular aptamers.
Enjoy
your visit here.
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Recent Publications in 2008: |
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Engineering
target-responsive hydrogels based on aptamer-target interactions.
Huanghao Yang, Haipeng Liu, Huaizhi Kang, and Weihong Tan.
J Am Chem Soc. 130(20):6320-1 (2008).
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Investigation
of the hybrid molecular probe for intracellular studies. Karen
Martinez, Colin D Medley, Chaoyong James Yang , Weihong Tan.
Anal Bioanal Chem. 391(3):983-91 (2008). |
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Molecular
assembly for high-performance bivalent nucleic acid inhibitor.
Youngmi Kim, Zehui Cao, Weihong Tan. Proc Natl Acad Sci U S
A. 105(15):5664-9 (2008). |
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Cell-specific
aptamer probes for membrane protein elucidation in cancer cells.
Dihua Shangguan, Zehui Cao, Ling Meng, Prabodhika Mallikaratchy,
Kwame Sefah, Hui Wang, Ying Li, Weihong Tan. J Proteome Res.
7(5):2133-9 (2008). |
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Molecular
Recognition of Small-Cell Lung Cancer Cells Using Aptamers.
Hui William Chen, Colin D Medley, Kwame Sefah, Dihua Shangguan,
Zhiwen Tang, Ling Meng, Josh E Smith, Weihong Tan. ChemMedChem.
Mar 13. [Epub ahead of print] (2008). |
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Cancer
cell targeting using multiple aptamers conjugated on nanorods.
Yu-Fen Huang, Huan-Tsung Chang, Weihong Tan. Anal Chem. 80(3):567-72
(2008). |
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Light-switching
excimer beacon assays for ribonuclease H kinetic study.
Yan Chen, Chaoyong James Yang, Yanrong Wu, Patrick Conlon, Youngmi
Kim, Hui Lin, Weihong Tan. Chembiochem. 15;9(3):355-9 (2008). |
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- The
Analytical Chemistry paper "Aptamer-Conjugated Nanoparticles
for the Collection and Detection of Multiple Cancer Cells" by
Josh E Smith, Colin Medley, Zhiwen Tang, Dihua Shangguan, Charles
Lofton, Weihong Tan was featured as a Most-Cited Article for 2006
and a Most-Accessed Article for 2007. [http://pubs.acs.org/journals/promo/most/most_cited/index.html]
- Youngmi Kim
was the sole winner of this year’s Herbert A. and Marjorie G.
Laitinen Graduate Fellowship. This award is
given to the best overall graduate students in their graduate studies.
- Yan Chen also
received the 2008 Roger G. and Jo Bates Graduate Fellowship.
- Youngmi
Kim and Prabodhika Mallikaratchy were both awarded 2007 Proctor &
Gamble Awards for their excellent research as well as the Chemistry
Department publication award.
- M-Carmen
Estévez has won 2nd Prize at the April, 2008 IAB Poster Competition
at UF for her poster, "Dye-doped silica nanoparticles as high-signal
amplification probe for cancer cell detection and targeting"
by M-Carmen Estévez, Meghan B O'Donoghue, and Weihong Tan.
- Prabodhika
Mallikaratchy has been awarded a 2007-2008 Ruegamer Fellowship along
with a Ruegamer Biochemistry Award. A Great Effort!
- Banished
Bacteria at the London Science Museum (2007).
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