A number of graduate-level biochemistry
courses are offered by the Division. To ensure that these courses
are accessible to both biochemistry majors and non-majors, none require
undergraduate-level biochemistry as a pre-requisite, although this experience
is helpful. It is strongly recommended that graduate students without
a strong biochemistry background take CHM 5305 (Chemistry of Biological
Molecules), which provides a one-semester overview of biochemistry.
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CHM 5305 - Chemistry of Biological
Molecules. This
course introduces the principles of biochemistry and integrates organic
mechanisms. It is strongly recommended for students interested in
joining a group in the Biochemistry Division and also for those whose research
in other groups will involve a strong biochemistry emphasis.
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CHM 6301 - Enzyme Mechanisms.
An introduction to principles of enzyme structure, isolation and characterization
of enzymes. Transition state theory, types of chemical catalysis
and cofactor chemistry are also discussed.
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CHM 6302 - Chemistry and Biology
of Nucleic Acids.
Principles of nucleic acid structure and function are discussed in the
context of recent research results. There is special emphasis on
sequence-specific protein-DNA binding, DNA and RNA polymerases, mechanisms
of phosphate chemistry and the chemical processes underlying nucleic acid
metabolism.
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CHM 6303 - Methods in Computational
Biochemistry and Structural Biology.
Approaches to protein structure, both modeled and experimental, are discussed
in the context of reaction mechanisms. Both empirical and quantum-mechanical
methods are covered. This course provides a good deal of practical
experience in applying computational methods and is recommended for students
planning to apply these techniques to their research.
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CHM 6304 - Special Topics in Biological
Chemistry Mechanisms.
Principles underlying protein structure prediction, molecular evolution,
rational protein design and molecular recognition are discussed.
This course offers a significant amount of hands-on computational
experience which will allow students to use these methods in their own
research.
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CHM 6934 - Advanced Biochemical
Topics (Journal Club).
This course provides an opportunity to examine recent research papers critically
and builds skills in effective oral presentations and experimental design.
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Last
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