The Chemistry and Biology of
Nucleic
Acids
 |
 |
|
 |
 |
 |
 |
|
| General information |
|
| Course
news 11/13/09 |
Suggested reading for the upcoming lecture
on the kinetic mechanism of DNA polymerase is now
available here. |
| Instructor |
Jon D. Stewart, 102
Leigh Hall, jds2@chem.ufl.edu |
| Lectures |
Monday,
Wednesday and Friday, 4th period (10:40 a.m. - 11:30 a.m.),
203 Little Hall |
| Office
hours |
Monday, 2nd period (8:30 a.m.- 9:20
a.m.) Wednesday, 5th period (11:45 a.m. - 12:35 p.m.) Friday, 2nd period (8:30 a.m.- 9:20 a.m.) and other mutually convenient times |
| Objectives |
This class will utilize specific examples to provide a general understanding of topics related to nucleic acids. In addition to discussions of DNA and RNA, lectures will also introduce students to biochemical mechanisms, the chemistry of phosphoryl transfer, protein-nucleic acid interactions and the use of kinetic studies to understand enzymes. |
| Prerequisites |
There are no prerequisites for this
course, apart from undergraduate organic chemistry (CHM 2210/2211, CHM
3217 or equivalent). An undergraduate biochemistry course will be
helpful, but not essential. |
| Classroom
attendance |
While attendance is
voluntary, the lectures are an essential component of the experience
for this
class. All of the reading material is derived from review
articles or
the primary research literature and the classroom lectures will explain
and
expand upon this material. |
| Reading
materials |
In general, lectures will be based on one
or two key references. Other papers that provide background
material or interesting extensions of the primary material will also be
given. The reading list will be posted on this web site
approximately one week prior to the lecture and copies of the papers
will also be available on-line. Exam questions will be based
only on what was covered in the lectures. In addition to
papers in the literature, students may also find the following general
references useful:
|
